diff --git a/python/Cargo.toml b/python/Cargo.toml
index 3cacf9bc..a63d6c89 100644
--- a/python/Cargo.toml
+++ b/python/Cargo.toml
@@ -18,15 +18,17 @@ name = "pyoxigraph"
 doctest = false
 
 [features]
-default = ["native-tls"]
 abi3 = ["pyo3/abi3-py38"]
-native-tls = ["oxigraph/http-client-native-tls"]
 rocksdb-pkg-config = ["oxigraph/rocksdb-pkg-config"]
-rustls = ["oxigraph/http-client-rustls-native"]
 
 [dependencies]
-oxigraph.path = "../lib"
 pyo3 = { version = "0.20.1", features = ["extension-module"] }
 
+[target.'cfg(any(target_family = "windows", target_os = "macos", target_os = "ios"))'.dependencies]
+oxigraph = { path = "../lib", features = ["http-client-native-tls"] }
+
+[target.'cfg(not(any(target_family = "windows", target_os = "macos", target_os = "ios")))'.dependencies]
+oxigraph = { path = "../lib", features = ["http-client-rustls-native"] }
+
 [lints]
 workspace = true
diff --git a/python/README.md b/python/README.md
index c8478a60..d9fae275 100644
--- a/python/README.md
+++ b/python/README.md
@@ -32,8 +32,8 @@ Pyoxigraph documentation is [available on the Oxigraph website](https://pyoxigra
 To build and install the development version of pyoxigraph you need to clone this git repository including submodules (`git clone --recursive https://github.com/oxigraph/oxigraph.git`)
 and to run `pip install .` in the `python` directory (the one this README is in).
 
-Note that by default the installation will not use [cpython stable ABI](https://docs.python.org/3/c-api/stable.html) and will rely on the host TLS implementation.
-Use `--features abi3` feature to use cpython stable ABI and use `--no-default-features --features rustls` to use [rustls](https://github.com/rustls/rustls) with the system certificates.
+Note that by default the installation will not use [cpython stable ABI](https://docs.python.org/3/c-api/stable.html).
+Use `--features abi3` feature to use cpython stable ABI.
 
 ## Help